I was watching a NOVA about Isaac Newton and I was highly amused that another member of the Royal Society was always trying to both discredit Newton's findings and yet claim that he had thought of them first. That's a nice trick.
But the best thing was when they spoke about Newton having a nervous breakdown which led to him attacking his few friends -- among them John Locke. He apparently accused Locke of trying to ply him with women.
I thought it would be hilarious if Locked had replied, "You just need to get laid."